Prognostication in Myelodysplastic Syndromes: Beyond the International Prognostic Scoring System (IPSS)

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[Revised international prognostic scoring system (IPSS-R) for myelodysplastic syndromes].

Peter L. Greenberg, Heinz Tuechler, Julie Schanz, Guillermo Sanz, Guillermo GarciaManero, Francesc Solé, John M. Bennett, David Bowen, Pierre Fenaux, Francois Dreyfus, Hagop Kantarjian, Andrea Kuendgen, Alessandro Levis, Luca Malcovati, Mario Cazzola, Jaroslav Cermak, Christa Fonatsch, Michelle M. Le Beau, Marilyn L. Slovak, Otto Krieger, Michael Luebbert, Jaroslaw Maciejewski, Silvia M.M. Maga...

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Application of the International Prognostic Scoring System for myelodysplastic syndromes.

BACKGROUND In March 1997 an international workshop introduced a new International Prognostic Scoring System (IPSS) for MDS. The goal of the present study was to apply the IPSS to a large group of MDS patients from one centre and to compare it to the FAB-classification. PATIENTS One hundred eighty-four MDS patients were included on the basis of similar criteria as used by the workshop but some...

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MYELOID NEOPLASIA Revised International Prognostic Scoring System for Myelodysplastic Syndromes

Peter L. Greenberg,1 Heinz Tuechler,2 Julie Schanz,3 Guillermo Sanz,4 Guillermo Garcia-Manero,5 Francesc Solé,6 John M. Bennett,7 David Bowen,8 Pierre Fenaux,9 Francois Dreyfus,10 Hagop Kantarjian,5 Andrea Kuendgen,11 Alessandro Levis,12 Luca Malcovati,13 Mario Cazzola,13 Jaroslav Cermak,14 Christa Fonatsch,15 Michelle M. Le Beau,16 Marilyn L. Slovak,17 Otto Krieger,18 Michael Luebbert,19 Jaros...

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International scoring system for evaluating prognosis in myelodysplastic syndromes.

Despite multiple disparate prognostic risk analysis systems for evaluating clinical outcome for patients with myelodysplastic syndrome (MDS), imprecision persists with such analyses. To attempt to improve on these systems, an International MDS Risk Analysis Workshop combined cytogenetic, morphological, and clinical data from seven large previously reported risk-based studies that had generated ...

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Perspectives in the prognostication of myelodysplastic syndromes.

Since the first precise definition of myelodysplastic syndromes (MDS) in 1982, prognostication of this disease has been a matter of debate. It very quickly became clear that the prognosis of MDS patients cannot be assessed by a single parameter, although the prognostic impact of the FAB classification, which is based on bone marrow morphology, is still impressive. This reflects the fact that th...

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ژورنال

عنوان ژورنال: The American Journal of Medicine

سال: 2013

ISSN: 0002-9343

DOI: 10.1016/j.amjmed.2012.08.013